منابع مشابه
Tissue concentrations of a long-acting oxytetracycline formulation after intramuscular administration in cattle.
The tissue distribution of a long-acting oxytetracycline formulation after intramuscular administration to calves at a dose rate of 20 mg/kg was studied. Oxytetracycline concentrations were determined in lung, bone marrow, mammary gland, uterus, uterine horn, ovary, liver, synovial fluid, joint tissue, kidney, spleen, brain, muscle, fat, urine, bile, saliva, ruminal content and serum. Observed ...
متن کاملVaginal concentrations of lactic acid potently inactivate HIV
OBJECTIVES When Lactobacillus spp. dominate the vaginal microbiota of women of reproductive age they acidify the vagina to pH <4.0 by producing ∼1% lactic acid in a nearly racemic mixture of d- and l-isomers. We determined the HIV virucidal activity of racemic lactic acid, and its d- and l-isomers, compared with acetic acid and acidity alone (by the addition of HCl). METHODS HIV-1 and HIV-2 w...
متن کاملSerum oxytetracycline concentrations in African elephant (Loxodonta africana) calves after long-acting formulation injection.
Serum oxytetracycline pharmacokinetics were studied in 18 African elephant (Loxodonta africana) calves. Each elephant received separate injections of oxytetracycline at approximately 18 mg/kg i.m. and 8 mg/kg i.v. in a cross-over study. Blood samples were drawn at 0, 24, 48, 72, and 96 hr postinjection. An additional sample was drawn 110 hr before the animals were reinjected in the cross-over s...
متن کاملssDNA aptamers that selectively bind oxytetracycline.
Single stranded DNA aptamers that bind with high affinity and specificity to the oxytetracycline (OTC) were identified by selection from an oligonucleotide library of 10(15) molecules. The binding affinities of four aptamers were in nanomolar range. The aptamers were highly selective in that, lack of -OH group at 5-position in tetracycline and -H group in place of -OH at 6-position in doxycycli...
متن کاملGenetics of Streptomyces rimosus, the oxytetracycline producer.
From a genetic standpoint, Streptomyces rimosus is arguably the best-characterized industrial streptomycete as the producer of oxytetracycline and other tetracycline antibiotics. Although resistance to these antibiotics has reduced their clinical use in recent years, tetracyclines have an increasing role in the treatment of emerging infections and noninfective diseases. Procedures for in vivo a...
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ژورنال
عنوان ژورنال: Sexually Transmitted Infections
سال: 1979
ISSN: 1368-4973
DOI: 10.1136/sti.55.5.348